Caspase 1

A long pro-domain caspase that has specificity for the precursor form of INTERLEUKIN-1BETA. It plays a role in INFLAMMATION by catalytically converting the inactive forms of CYTOKINES such as interleukin-1beta to their active, secreted form. Caspase 1 is referred as interleukin-1beta converting enzyme and is frequently abbreviated ICE.

Also Known As:

ICE Protease; CASP1 Caspase; IL-1 beta Convertase; IL1BC Enzyme; Interleukin-1 Converting Enzyme; Pro-Caspase-1; Procaspase-1; Caspase, CASP1; Convertase, IL-1 beta; Converting Enzyme, Interleukin-1; Converting Enzyme, Interleukin-1beta; IL 1 beta Convertase; IL 1 beta Converting Enzyme; Interleukin 1 Converting Enzyme; Interleukin 1beta Converting Enzyme; Pro Caspase 1; Procaspase 1; beta Convertase, IL-1; beta-Converting Enzyme, IL-1; IL-1 beta-Converting Enzyme; Interleukin-1beta Converting Enzyme

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Peptide Hydrolases: 23957
      - Cysteine Proteases: 1964
        Cysteine Endopeptidases: 4
        Caspases: 9379
        Initiator Caspases: 34
        Caspase 1: 989
      - Endopeptidases: 633
        Cysteine Endopeptidases: 4
        Caspases: 9379
        Initiator Caspases: 34
        Caspase 1: 989
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intracellular Signaling Peptides and Proteins: 32
    - Apoptosis Regulatory Proteins: 2514
      - Caspases: 9379
        Initiator Caspases: 34
        Caspase 1: 989

Rick Shapiro Selected Research

Rick Shapiro Research Topics

Disease

Drug/Important Bio-Agent (IBA)

Therapy/Procedure